What is Colocalization Analysis
Colocalization refers to the ability to detect and quantify the overlap or proximity of two or more distinct signals, typically fluorescence-based, within a sample. It is used to identify markers that are spatially associated on particles or molecules, such as EVs liposomes, and other nanoparticles.
This technique is particularly valuable for understanding the composition and purity of samples, enabling researchers to study co-expressed markers, binding events, or the structural organization of biological or synthetic systems.mKey Attributes of Colocalization:
Spatial Analysis: Measures the overlap of fluorescence signals to determine the simultaneous presence of multiple biomarkers.
Quantitative Insights: Provides numerical data on the degree of colocalization, enabling accurate comparisons.
Multi-Channel Capabilities: Simultaneously analyze multiple fluorescent markers within a single sample